Non-specific immune system enhancement

Details Non-specific immune system enhancement Non-specific immune system enhancement

1990-03-29

1992-09-15

Hafer, Robert A.

Surgery

Blood drawn and replaced or treated and returned to body

604 20, 424 90, A61M 3700

Patent

active

051472899

ABSTRACT:
The present invention pertains to a method for non-specifically enhancing the immune system response of a mammal to an antigen which comprises the steps of (a) withdrawing leukocyte containing material from the mammal, (b) treating the withdrawn leukocytes in a manner to alter the cella, and (c) returning the treated leukocytes to the mammal. The one embodiment, the method for non-specifically enhancing the immune system response of a mammal is carried out in conjunction with artificially contacting the mammal's immune system with an antigen for a suitable period of time to stimulate the immune system. In another embodiment, the mannal's immune system is naturally exposed to the antigen prior to the non-specific enhancement of the immune system. In yet another embodiment, the invention is directed at a method for preparing an autologous non-specific leukocyte adjuvant.

REFERENCES:
patent: 4634417 (1987-01-01), Korec
patent: 4664913 (1987-05-01), Mielke et al.
patent: 4824432 (1989-04-01), Skurkovich et al.
patent: 4955857 (1990-09-01), Shettigar
patent: 4960408 (1990-10-01), Klainer et al.

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