Non-ribosomal peptide synthetases and associated...

Details Non-ribosomal peptide synthetases and associated... Non-ribosomal peptide synthetases and associated...

2006-02-17

2008-03-11

Nashed, Nashaat T. (Department: 1656)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S252350, C435S252330, C435S325000, C435S410000, C435S320100, C536S023200

Reexamination Certificate

active

07341861

ABSTRACT:
The present invention describes the identification of novel non-ribosomal peptide synthetases and associated biosynthetic genes fromStreptomyces hygroscopicus. The present invention further provides methods for generating novel compounds, such as antibiotics, from these synthetases and associated genes.

REFERENCES:
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patent: WO 00/40704 (2000-01-01), None
patent: WO 00/20601 (2000-04-01), None
patent: WO 02/24736 (2002-02-01), None
patent: WO 02/077179 (2002-10-01), None
patent: WO 02/101051 (2002-12-01), None
Marahiel et al., Chem Rev. 1997; 97: 2651-73.
Stachelhaus et al., Chemistry and Biology 1999; 6:493-505.

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