Non-reactive composite sealing barrier

Surgery – Container for blood or body treating material – or means used...

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215DIG3, 215364, B65D 8500

Patent

active

052796060

ABSTRACT:
An elastomeric pharmaceutical barrier (2, 50, 75, 100) formed as a piston, a stopper, or a cap-like gasket and diaphragm structure for use in pharmaceutical containers such as vials, syringes, cartridges and the like. The barrier combines a main body (4, 52, 76, 102) of butyl or silicone based rubber to provide a fluid seal mechanism and includes a pharmaceutically inert insert (6, 54, 78, 104) which provides a substantial portion (40, 68, 92, 130) of a surface of the barrier to be exposed to the pharmaceutical. The non-reactive insert can be fabricated from polytetrafluoroethylene, glass, stainless steel or ceramic material and reduces the surface area of rubber exposed to pharmaceutical contact, therefore making the applicable face of the barrier substantially inert and nonreactive to the contacting pharmaceutical. The insert can be made to incorporate a guide (62, 66) and channel (64) for needle canula (74) access as well as a pressure valve system (118, 126, 132, 136) to allow fluid flow through the barrier structure.

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