Non-porous diagnostic devices for the controlled movement of rea

Details Non-porous diagnostic devices for the controlled movement of rea Non-porous diagnostic devices for the controlled movement of rea

1997-03-03

2000-11-07

Housel, James C.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

422 56, 422 57, 422 58, 422 60, 435 71, 435 792, 435 793, 4352872, 436523, 436525, 436527, 436530, 436533, 436541, 436810, 436818, G01N 33533

Patent

active

061435767

ABSTRACT:
The assay devices, assay systems and device components of this invention comprise at least two opposing surfaces disposed a capillary distance apart, at least one of which is capable of immobilizing at least one target ligand or a conjugate in an amount related to the presence or amount of target ligand in the sample from a fluid sample in a zone for controlled fluid movement to, through or away the zone. The inventive device components may be incorporated into conventional assay devices with membranes or may be used in the inventive membrane-less devices herein described and claimed. These components include, flow control elements, measurement elements, time gates, elements for the elimination of pipetting steps, and generally, elements for the controlled flow, timing, delivery, incubation, separation, washing and other steps of the assay process.

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