Non-polar media for polynucleotide separations

Details Non-polar media for polynucleotide separations Non-polar media for polynucleotide separations

1998-10-30

2000-05-02

Therkorn, Ernest G.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210659, 2101982, 210656, 435 6, 536 231, 536 254, B01D 1508

Patent

active

060568771

ABSTRACT:
Nonporous beads having an average diameter of about 0.5-100 microns are suitable for chromatographic separation of mixtures of polynucleotides when the beads comprise a nonporous particle which are coated with a polymer or which have substantially all surface substrate groups endcapped with a non-polar hydrocarbon or substituted hydrocarbon group. The beads provide efficient separation of polynucleotides using Matched Ion Polynucleotide Chromatography.

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