Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides with at least one nonpeptide bond other than a...
Patent
1985-02-19
1987-01-20
Foelak, Morton
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Peptides with at least one nonpeptide bond other than a...
530335, 530337, 528328, 424 19, 424 26, 424 36, 424 78, 604891, 604892, C07K 106
Patent
active
046380450
ABSTRACT:
A novel bioerodible polymeric composition is provided comprising a plurality of monomer units of two or three amino acids which are polymerized via hydrolytically labile bonds at their respective side chains rather than at the amino or carboxylic acid terminals by amide bonds. Such polymers are useful for controlled release applications in vivo and in vitro for delivery of a wide variety of biologically and pharmacologically active ligands.
REFERENCES:
patent: 3773737 (1973-11-01), Goodman et al.
patent: 4385189 (1983-05-01), Kato et al.
patent: 4511478 (1985-04-01), Nowinski et al.
Kohn Joachim
Langer Robert S.
Cook Paul J.
Draper Garnette D.
Foelak Morton
Massachusetts Institute of Technology
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