Surgery – Miscellaneous – Methods
Patent
1998-05-07
2000-10-24
Millin, Vincent
Surgery
Miscellaneous
Methods
607 88, A61B 1900
Patent
active
061351172
ABSTRACT:
A method for resetting the phase of the human circadian clock and for enhancing alertness and performance in humans. The method involves the application of non-solar photic stimulation, in the range of 15 to 150,000 lux, to any non-ocular region of the human body during wakefulness or during sleep. Preferably, the photic stimulation has a wavelength within the visible spectrum (.about.400-750 nm). The method can be used to both delay and advance the circadian clock according to a phase response curve (PRC). The method may also be used for acute/immediate enhancement of alertness and performance. The method is applicable to alleviation of problems associated with "jet-lag", shift work sleep disturbance, and other sleep disturbances involving misalignment of circadian rhythms. The method provides a novel technique for shifting the phase of the circadian clock, and enhancing alertness and performance, using existing, or newly-developed devices.
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Campbell Scott S.
Murphy Patricia J.
Cornell Research Foundation Inc.
Millin Vincent
O'Hara Kelly
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