Non-nucleoside reverse transcriptase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S388000, C514S045000, C514S395000, C514S248000, C546S123000, C546S118000, C548S306400, C544S236000

Reexamination Certificate

active

07947709

ABSTRACT:
Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

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Chan, J. H., wt. al. “Novel Benzophenones as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1,”J. Med. Chem.2004, vol. 47, pp. 1175-1182.
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