Non-mutagenic 1,2-disubstituted 4-nitro-imidazoles useful as ant

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548338, A61K 31415, C07D23391

Patent

active

046753370

ABSTRACT:
The invention relates to novel 1,2-disubstituted-4-nitroimidazole compounds that are useful as potent antiprotozoal agents and simultaneously possess non-mutagenicity as compared to known 4- or 5-nitroimidazole compounds. Also, compositions and methods for antiprotozoal uses of said novel 1,2-disubstituted-4-nitroimidazole compounds are disclosed herein.

REFERENCES:
patent: 3644392 (1972-02-01), Henry
Indian Journal of Chemistry, Section B, 21B(11), pp. 1006-1021 (1982).

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