Non-mammalian DNA virus to express an exogenous gene in a mammal

Details Non-mammalian DNA virus to express an exogenous gene in a mammal Non-mammalian DNA virus to express an exogenous gene in a mammal

1995-06-07

1998-03-24

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

4353201, 435 691, 435 701, C12N 900, C12N 1563, C12P 2102

Patent

active

057311820

ABSTRACT:
Disclosed is a method of expressing an exogenous gene in a mammalian cell, involving infecting the cell with a non-mammalian virus (e.g., a baculovirus) whose genome carries an exogenous gene, and growing the cell under conditions such that the gene is expressed. Also disclosed is a method of treating a gene deficiency disorder in a mammal by providing to a cell a therapeutically effective amount of a virus whose genome carries an exogenous gene and growing the cell under conditions such that the exogenous gene is expressed in the mammal.

REFERENCES:
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