Non-M, non-O HIV-1 strains, fragments and uses

Details Non-M, non-O HIV-1 strains, fragments and uses Non-M, non-O HIV-1 strains, fragments and uses

2006-04-18

2006-04-18

Housel, James (Department: 1648)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S024300, C536S024330, C514S04400A, C424S187100, C435S975000, C435S005000, C435S006120, C435S235100

Reexamination Certificate

active

07030234

ABSTRACT:
Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBF30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent.The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics:little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV;absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups;genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; andhomology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.

REFERENCES:
patent: 86/02383 (1986-04-01), None
patent: 94/28915 (1994-12-01), None
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Tojo, et al., “Cloning and nucleotide sequence of theMyxococcus xanthus longene: indispensibility oflonfor vegetative growth”, Journal of Bacteriology, vol. 175, No. 8, Apr., 1993, pp. 2271-2277.

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