Non-irritating dentifrice

Details Non-irritating dentifrice Non-irritating dentifrice

1992-07-02

1994-03-08

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424 49, 424 52, 424 57, A61K 716, A61K 718, A61K 722

Patent

active

052925021

ABSTRACT:
An oral composition of acceptable taste substantially non-irritating to oral tissue, the composition containing an effective amount of a sodium lauryl sulfoacetate surfactant purified to contain less than 18% by weight impurities. An amount of a nonionic or amphoteric compound is included in the composition to enhance the foaming ability of the purified sodium lauryl sulfoacetate surfactant as well as to further reduce its irritancy potential.

REFERENCES:
patent: 3696192 (1972-10-01), Embring
patent: 3954962 (1976-05-01), Prussin
patent: 3957967 (1976-05-01), L'Orange
patent: 4391798 (1983-07-01), Tavss et al.
patent: 4405599 (1983-09-01), Smigel
patent: 4603045 (1986-07-01), Smigel
patent: 5000939 (1991-03-01), Dring et al.
patent: 5041280 (1991-08-01), Smigel
Schoenrock et al., CA. 115:282523g (1991) of Ger DE 4007638 Sep. 12, 1991.
Takahashi CA. 112:124914b (1990) of JPN 01211521 Aug. 24, 1989.
Final Report CA. 108:101090h (1988) of J. Am. Coll. Toxicol. 6(3):261-277(1987).
Levi et al., CA. 86:18726b (1977).
Wakeman CA. 83:103158a (1975) of Fr. lemonde 2229389 Dec. 13, 1974.
Schultz CA. 76:76368r (1972) of Amer. Met. Perfume 87(1):29-32 (1972).
Janistyn et al., CA. 74:102992p (1971) of Ger DE 1943441 Mar. 4, 1971.
Embring CA. 73:112987r (1970) of Ger DE 2008694 Feb. 27, 1969.

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