Non-invasive system and method for measuring skin hydration...

Surgery – Diagnostic testing – Sensitivity to thermal stimulus

Reexamination Certificate

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C600S306000, C600S316000, C600S346000, C600S347000

Reexamination Certificate

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08043227

ABSTRACT:
A non-invasive system and method for measuring skin hydration of a subject includes a thermistor used in transient mode to obtain a measurement of the thermal conductivity of the skin of the subject and a processor for determining a skin hydration value from the thermal conductivity measurement. The system for measuring skin hydration further includes a non-invasive system for detecting blood analyte concentration, such as glucose, with a spectroscopic device having e.g., an infrared source which generates infrared beam and detector for detecting transmitted radiation through portion (e.g., finger) of a subject. The system may also include skin hydrator which moisturizes the skin and is connected in a control loop to the system for measuring skin hydration. The system for detecting blood analyte concentration may include a photoacoustic device or a metabolic heat conformation device.

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A. Dittmar, et al: Non Invasive Characterization of Skin Using Micro Thermal Diffusion Sensor, Engineering in Medicine and Biology Society, 1995. IEEE 17th Annual Conference, vol. 2, Sep. 20, 1995, Sep. 23, 1995, pp. 1569-1570.
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O. K. Cho, et al: “Noninvasive Measurement of Glucose by Metabolic Heat Conformation Method”; Clinical Chemistry 50:10, 2004, pp. 1894-1898.

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