Non-invasive methods of using spectral information in...

Details Non-invasive methods of using spectral information in... Non-invasive methods of using spectral information in...

2007-08-21

2009-10-13

Winakur, Eric F (Department: 3768)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C600S322000, C600S316000

Reexamination Certificate

active

07603151

ABSTRACT:
A non-invasive method of determining the concentration of an analyte uses Raman or fluorescence spectral information. A high-intensity band of light is applied to one side of skin tissue. The high-intensity light enters the skin tissue and generates a Raman or fluorescence signal. A Raman-generating material or fluorescence-generating material is placed in a location nearest the other side of skin tissue. The Raman-generating or fluorescence-generating material is located generally opposite of the entry of the applied high-intensity light. The Raman or fluorescence signal is collected and the analyte concentration is determined using the collected Raman signal.

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