Non-invasive in vivo pressure measurement

Details Non-invasive in vivo pressure measurement Non-invasive in vivo pressure measurement

1998-06-12

2000-07-11

Jaworski, Francis J.

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

600561, A61B 800

Patent

active

060865334

ABSTRACT:
Apparatus and methods are disclosed for non-invasive measurement of blood velocity in otherwise inaccessible body regions, and for correlating such measurements with externally applied pressure to detect and/or assess diseases or physiological abnormalities. The blood velocity measurements can be based on the Doppler shift that occurs when an ultrasonic wave is scattered by moving particles within the blood. Since blood vessels have elastic walls, the geometry of the walls, and therefore the flow dynamics, will change in response to elevated in vivo pressure. The change in resistance to blood flow resulting from these pressure induced changes to the blood vessel wall geometry can provide a measure of intracranial pressure, ophthalmic pressure or various other body conditions that affect blood perfusion. Since the blood vessel wall geometry changes rapidly in response to such changes in pressure, the invention can be used to detect hydrocephalus, retinopathy, papilledema and other physiological abnormalities manifested by pressure changes.

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