Non-invasive gene targeting to ocular cells

Details Non-invasive gene targeting to ocular cells Non-invasive gene targeting to ocular cells

2006-08-15

2006-08-15

Ketter, James (Department: 1636)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C424S009100, C424S009200

Reexamination Certificate

active

07090864

ABSTRACT:
Liposomes containing therapeutic genes are conjugated to multiple targeting agents to provide transport of the encapsulated gene across the blood-retinal barrier and the plasma membrane of ocular cells. Once across the blood-retinal barrier and ocular cell membrane, the encapsulated gene expresses the encoded therapeutic agent within the ocular cells to provide diagnosis and/or treatment of disease.

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