Multicellular living organisms and unmodified parts thereof and – Method of using a transgenic nonhuman animal in an in vivo...
Reexamination Certificate
1999-12-16
2008-11-11
Falk, Anne-Marie (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Method of using a transgenic nonhuman animal in an in vivo...
C800S018000
Reexamination Certificate
active
07449615
ABSTRACT:
The present invention relates to panels of reporter expression cassettes and the generation of transgenic non-human animals, wherein said reporter expression cassettes have selected control elements operable linked to reporter genes. The invention includes methods of use thereof for the identification and characterization of the effects of compounds administered to the live transgenic non-human animals.
REFERENCES:
patent: 5650135 (1997-07-01), Contag et al.
patent: 6020121 (2000-02-01), Bao et al.
patent: 6217847 (2001-04-01), Contag et al.
patent: 0123456 (2000-01-01), None
patent: WO 93/23533 (1993-11-01), None
patent: WO 96/40979 (1996-12-01), None
patent: WO 97/11690 (1997-04-01), None
patent: WO 97/11690 (1997-04-01), None
patent: WO 97/18841 (1997-05-01), None
patent: WO 97/40381 (1997-10-01), None
patent: WO 98/28971 (1998-07-01), None
patent: WO 98/36081 (1998-08-01), None
patent: WO 99/11772 (1999-03-01), None
patent: WO 99/11772 (1999-03-01), None
patent: WO 99/37142 (1999-07-01), None
patent: WO 00/36106 (2000-06-01), None
patent: WO 00/54581 (2000-09-01), None
patent: WO 00/54581 (2000-09-01), None
patent: WO 01/18195 (2001-03-01), None
patent: WO 01/18225 (2001-03-01), None
patent: WO 01/37195 (2001-05-01), None
C. Cui et al., Transgenic Research, “Reporter genes in transgenic mice,” Review, 1994, 3, pp. 182-194.
R. E. Hammer et al., Cell Press, “Spontaneous Inflammatory disease in transgenic rats expressing HLA-B27 and Human beta2m: An animal model of HLA-B27-associated human disorders,” Nov. 1990, vol. 63,pp. 1099-1112.
J. J. Mullins et al., Hypertension, “Transgenesis in Nonmurine Species,” 1993, 22, pp. 630-633.
E.R. Cameron, “Recent Advances in Transgenic Technology,” Molecular Biotechnology, 1997, vol. 7, pp. 253-265.
A.L. Boyd et al., “Review: Molecular Biology of Transgenic Animals,” J.Anim. Sci. 1993, 71(Suppl.3), 1-9.
Shibahara et al. Eur J Bichem 179 :557-563, 1989, abstract only.
Wood (Comparative Medicine 50 (1): 12-15, 2000.
Contag et al. Journal of Perinatology 21:S119-S124, 2001.
JAX Mice Price List, Jun. 1997, p. 19 (The Jackson Laboratory, Bar Harbor, Maine).
Mayerhofer et al., “Monitoring of Spatial Expression of Firefly Luciferase in Transformed Zebrafish,”J Biolumin Chemilumin10:271-275, 1995.
Zhang et al., “Bioluminescence For Biological Sensing in Living Mammals,”Adv. Exper. Med. Biol. 471:775-784, 1999.
Contag et al., “Visualizing Gene Expression in Living Mammanls Using a Bioliminescent Reporter,”Photochemistry and Photobiology66(4):523-531, 1997.
Contag Pamela R.
Zhang Ning
Falk Anne-Marie
Robins & Pasternak LLP
Xenogen Corporation
LandOfFree
Non-invasive evaluation of physiological response in a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-invasive evaluation of physiological response in a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-invasive evaluation of physiological response in a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4021857