Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1992-06-15
1995-08-08
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4241841, 4241851, 4241861, 4241871, 4241881, 4242041, 4242071, 4242081, 435 691, 4351723, 435 701, 435 711, 435236, 4352351, 435974, 530350, 530826, 536 231, 536 2372, 514 2, A61K 3921, C12N 1549, C07K 14155
Patent
active
054398096
ABSTRACT:
An immunogenic HIV retrovirus-like particle which is non-infectious and non-replicating and which is useful as a candidate vaccine component against HIV infection, is produced by genetic engineering. A DNA molecule comprising the HIV genome devoid of long terminal repeats is incorporated into an expression vector, which is introduced into mammalian cells for expression of the HIV retrovirus-like particle.
REFERENCES:
patent: 4722840 (1988-02-01), Valenzuela et al.
Hu, S. L. et al. 1986 Nature 320:537-540.
Gheysen, D. et al. 1989. Cell 59:103-112.
Varmus, H. 1988 Science 240:1427-1435.
Desrosiers, R. C. et al, 1989. Proc. Nalt. Acad. Sci. 86:6353-6357.
Bowie, J. V. et al. 1990, Science 247:1306-1310.
Lu, Y. et al. J. of Virology 63(9):4115-4119.
Sambrook, J. et al. Molecular Cloning, Cold Spring Harbor Lab Press (1989) pp. 16.7-16.72.
Cao Shi X.
Haynes Joel
Klein Michel H.
Rovinski Benjamin
Connaught Laboratories Limited
Nucker Christine M.
Tuscan M. S.
LandOfFree
Non-infectious HIV particles lacking long terminal repeats does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-infectious HIV particles lacking long terminal repeats, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-infectious HIV particles lacking long terminal repeats will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-970600