Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-01-15
2008-01-15
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S250000, C544S251000
Reexamination Certificate
active
11170265
ABSTRACT:
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain non-imidazole tertiary amine derivatives and their salts and solvates. These compounds have H3histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3receptor blockade is beneficial.
REFERENCES:
patent: 7034153 (2006-04-01), Nakai et al.
Bertaccini, G., et al., Review Article: the Histamine H3-receptor: a Novel Prejunctional Receptor Regulating Gastrointestinal Function, Aliment. Pharmacol. Therap. (1991) 5, 585-591.
V. A. Makarov et al., Chemistry of Heterocyclic Compounds, vol. 34, No. 12, 1998, “Synthesis of Pyrazolo[1,5-a] Pyrimpdines by the Reaction of β-Dicarbonyl Compounds with 3,5-Diamino-4-Nitropyrazole” 1999 Kluwer Academic/Plenum Publishers.
Anderson James T.
Bennani Youssef L.
Campbell Michael G.
Wang Jianmin
Athersys, Inc.
Leeser Erich
Wilson James O.
Wood Phillips Katz Clark & Mortimer
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