Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-03-22
2011-03-22
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S408000
Reexamination Certificate
active
07910605
ABSTRACT:
Use of a compound of formula (A), wherein:W is a residue which imparts antagonistic and/or agonistic activity at histamine H3-receptors when attached to an imidazole ring in 4(5) position; R1and R2may be identical or different and represent each independently a lower alkyl or cycloalkyl, or taken together with the nitrogen atom to which they are attached, a saturated nitrogen-containing ring (i) as defined, a non-aromatic unsaturated nitrogen-containing ring (ii) as defined, a morpholino group, or a N-substituted piperazino group as defined for preparing medicaments acting as antagonists and/or agonists at the H3-receptors of histamine.
REFERENCES:
patent: 7138413 (2006-11-01), Schwartz et al.
patent: 7169928 (2007-01-01), Schwartz et al.
Seddon “Pseudopolymorph” . . . Crystal growth & design v. 496) p. 1087 (2004) (two pages from internet).
Braga et al. “Making crystals from crystals . . . ” Chemm. Commun. p. 3635-3645 (2005).
Ligneau et al. “BF2.649 . . . ” J. PHarmacol. Exp. ther. v. 329(1) p. 365-375 (2007).
Arrang Jean-Michel
Elz Sigurd
Ganellin Charon Robin
Garbarg Monique
Lecomte Jeanne-Marie
Chang Celia
Schulman B. Aaron
Societe Civile Bioprojet
Stites & Harbison PLLC
Wright Terry L.
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