Non-human transgenic animals expressing platelet-derived...

Details Non-human transgenic animals expressing platelet-derived... Non-human transgenic animals expressing platelet-derived...

2006-04-25

2006-04-25

Woitach, Joseph (Department: 1635)

Multicellular living organisms and unmodified parts thereof and

Method of using a transgenic nonhuman animal in an in vivo...

C800S008000, C800S018000, C800S021000, C800S024000, C800S025000, C435S007210, C435S004000, C435S354000

Reexamination Certificate

active

07034200

ABSTRACT:
Non-human transgenic animals overexpressing PDGF-C and cells thereof have been created. The transgenic animals contain a nucleotide sequence that encodes for platelet derived growth factor C (PDGF-C) or an analog thereof, or a functional fragment of PDGF-C or analog thereof. These animals are useful for studying disease states characterized by overexpression of PDGF-C, as well as useful for evaluating therapies intended to treat such diseases.

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