Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1994-09-26
1998-09-22
Crouch, Deborah
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
800DIG5, 4351723, 424 91, C12N 500, C12N 1500, A61K 4800
Patent
active
058116320
ABSTRACT:
A method for producing a mammalian model for papillomavirus infection by engrafting a portion of human skin onto a transplant-tolerant non-human mammal, inoculating the engrafted human skin with a papillomavirus genomic DNA such that a papillomavirus infection develops in the engrafted human skin or human skin cells. The non-human mammals are then used to identify compounds and therapies effective against papillomavirus infections.
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