Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1992-04-29
1994-05-31
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
4353201, 435221, 435222, 536 232, 935 10, 935 14, C12N 1500, C12N 954, C12N 956
Patent
active
053169417
ABSTRACT:
There are described certain DNA sequences which encode subtilisins wherein the amino acid sequence of such substilisins has been modified at a position equivalent to +225 in Bacillus amyloliquefaciens, such that an amino acid selected from the group consisting of alanine, leucine, methionine, glutamine, valine and serine, has been substituted for the amino acid residues naturally occuring at such position.
REFERENCES:
patent: 4760025 (1988-07-01), Estell et al.
Bott et al., J. Biol. Chem., vol. 263, No. 16, Jun. 5, 1988, pp. 7895-7906.
McPhalen et al., Biochemistry, vol. 27, 1988, pp. 6582-6598.
Bott Richard R.
Caldwell Robert M.
Estell David A.
Graycar Thomas P.
Genencor, Inc.
Hendricks Keith D.
Horn Margaret A.
Wax Robert A.
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