Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Biocides; animal or insect repellents or attractants
Patent
1994-10-03
1997-11-18
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Biocides; animal or insect repellents or attractants
424405, 424423, 514566, 514836, 604 53, A01N 2508, A01N 3712, A61F 202, A61M 3100
Patent
active
056885164
ABSTRACT:
Compositions and methods of employing compositions in flushing and coating medical devices are disclosed. The compositions include selected combinations of a chelating agent, anticoagulant, or antithrombotic agent, with an non-glycopeptide antimicrobial agent, such as the tetracycline antibiotics. Methods of using these compositions for coating a medical device and for inhibiting catheter infection are also disclosed. Particular combinations of the claimed combinations include minocycline or other non-glycopeptide antimicrobial agent together with EDTA, EGTA, DTPA, TTH, heparin and/or hirudin in a pharmaceutically acceptable diluent.
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Raad Isaam
Sherertz Robert
Azpuru Carlos
Baylor College of Medicine
Board of Regents , The University of Texas System
Wake Forest University
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