Non-crystalline minoxidil composition

Details Non-crystalline minoxidil composition Non-crystalline minoxidil composition

1989-04-04

1991-07-09

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

264 41, 424 11, 424 70, 424450, 4284022, 514 78, 514256, 514880, 514947, 514969, 514975, 514944, A61K 706, A61K 31505

Patent

active

050304429

ABSTRACT:
An aqueous, noncrystalline minoxidil composition for topical use which has significantly improved flux of the drug through human cadaver skin. The composition contains minoxidil complexed with an amphipathic compound, oleic acid and with pharmaceutically acceptable excipients. The composition may be formulated in an aqueous vehicle, or dispersed in fluorochlorocarbon solvent for spray delivery from a self- propelled spray device.

REFERENCES:
patent: 3413400 (1968-11-01), Lee
patent: 4073943 (1978-02-01), Wretlind et al.
patent: 4156719 (1979-05-01), Sezaki et al.
patent: 4654354 (1987-03-01), Shroot et al.
patent: 4670185 (1987-06-01), Fujiwara et al.
patent: 4828837 (1989-05-01), Uster et al.

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