Non-crosslinked protein particles for therapeutic and diagnostic

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Coated – impregnated – or colloidal particulate

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424 129, 424 137, 424484, 424499, 424 214, 424 221, 4242133, 42421333, 4284022, 42840224, 435177, 935 54, A61K 5108, A61K 950, B01J 1308, C12N 1102

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active

056163118

ABSTRACT:
Albumin particles in the nanometer and micrometer size range in an aqueous suspension are rendered stable against resolubilization without the aid of a crosslinking agent and without denaturation, by the incorporation of hemoglobin in the particle composition. Particles which are primarily hemoglobin in the nanometer and micrometer size range in an aqueous suspension are rendered stable against aggregation by the incorporation of either albumin, surface active agents or gelatin.

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