Non-competitive threshold ligand-receptor assays

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 75, 435 79, 435 792, 435 794, 435967, 436501, 436514, 436518, 436523, 436524, 436525, 436526, 436807, G01N 3353, G01N 33566, G01N 33558, G01N 33543

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059392720

ABSTRACT:
Assay methods for performing non-competitive ligand-receptor assays, where said assays provide a sensible result when the target ligand identified by the assay is present at a concentration greater than a defined threshold concentration. The threshold concentration can be selected to be the upper limit of a normal range of values for a target ligand in a sample, so that an assay in accordance with the invention provides a sensible result only when the target ligand is present at elevated levels.

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