Non-cariogenic composition and drink

Details Non-cariogenic composition and drink Non-cariogenic composition and drink

1992-05-12

1993-07-06

Nutter, Nathan M.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Rodent cell, per se

435885, C12N 120

Patent

active

052253449

ABSTRACT:
Non-cariogenic composition, which comprises as active ingredient the living cells of a Human type strain of Streptococcus mutans capable of inhibiting the growth of cariogenic strains of S. mutans and incapable of inducing dental caries, in association with a carrier or excipient suitable for oral administration, said strains of S. mutans being isolated from the oral cavity of humans as naturally-occuring strains. The non-cariogenic composition may be administered orally in the form of liquid, semi-solid or solid compositions, preferably in the form of yogurts containing edible lactic acid-producing bacilli or in the form of a freeze-dried composition containing such edible lactic acid-producing bacilli. The non-cariogenic composition may prevent or at least inhibit human dental caries induced by cariogenic S. mutans and moreover effective against other cariogenic oral bacilli such as edible lactic acid-producing bacilli known per se. Direct administration to human oral cavity may be effected simply and safely since the used effctor strains are naturally-occuring strains in the oral cavity of humans.

REFERENCES:
patent: 4521513 (1985-06-01), Russell
Krasse "Human Streptococci and Experimental Caries in Hamsters", Arch. oral Biol. vol. 11, pp. 429-436, 1966.
Ellwood et al. "Growth of Streptococcus Mutans in a Chemostat", Archs oral Biol vol. 19, pp. 659-664, 1964.

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