Non-cariogenic composition and drink

Details Non-cariogenic composition and drink Non-cariogenic composition and drink

1991-11-25

1992-08-04

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Dentifrices

Ferment containing

424 92, 424 93H, A61K 728, A61K 3902, A01N 6300

Patent

active

051357399

ABSTRACT:
Non-cariogenic composition, which comprises as active ingredient the living cells of a Human type strain of Streptococcus mutans capable of inhibiting the growth of cariogenic strains of S. mutans and incapable of inducing dental caries, in association with a carrier or excipient suitable for oral administration, said strains of S. mutans being isolated from the oral cavity of humans as naturally-ocuring strains. The non-cariogenic composition may be administered orally in the form of liquid, semi-solid or solid compositions, preferably in the form of yougurts containing edible lactic acid-producing bacilli or in the form of a freeze-dried composition containing such edible lactic acid-producing bacilli. The non-cariogenic composition may prevent or at least inhibit human dental caries induced by cariogenic S. mutans and moreover effective against other cariogenic oral bacilli such as edible lactic acid-producing bacilli known per se. Direct administration to human oral cavity may be effected simply and safely since the used effector strains are naturally-occurring strains in the oral cavity of humans.

REFERENCES:
patent: 1851165 (1932-03-01), Farr
patent: 1899817 (1933-02-01), Matt
patent: 2944941 (1960-07-01), Goldenberg
patent: 4133875 (1979-01-01), Hillman
patent: 4147773 (1979-04-01), Ogasa
patent: 4314995 (1982-02-01), Hata et al.
patent: 4337314 (1982-06-01), Oeschger et al.
patent: 4345032 (1982-08-01), Hata
patent: 4396631 (1983-08-01), Adachi et al.
patent: 4442085 (1984-04-01), Colman et al.
The Journal of Dental Health, vol. 28 No. 2, JPA 47970/82, including English translation.

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