Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2011-07-05
2011-07-05
Balasubramanian, Venkataraman (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C514S248000
Reexamination Certificate
active
07973159
ABSTRACT:
The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I.where R1, R1a, R1b, A, R3, R4, R5, R5band R6are as defined herein.
REFERENCES:
patent: 2007/0093509 (2007-04-01), Washburn et al.
patent: 2009/0298794 (2009-12-01), Washburn et al.
patent: WO 03/033476 (2003-04-01), None
patent: WO 2005/042541 (2005-05-01), None
patent: WO 2005/103039 (2005-11-01), None
patent: WO 2007/011284 (2007-01-01), None
patent: WO 2007/011286 (2007-01-01), None
Banker, G.S. et al., eds., Modern Pharmaceutics, Third Edition, pp. 451 and 596, Marcel Dekker, Inc., publ. (1996).
Vippagunta, S.R. et al., “Crystalline solids”, Advanced Drug Delivery Reviews, vol. 48, pp. 3-26 (2001).
West, A.R., Solid State Chemistry and its Applications, pp. 358 and 365, John Wiley & Sons, publ. (1988).
Wolff, M.E., ed., Burger's Medicinal Chemistry and Drug Discovery, Fifth Edition, vol. 1: Principles and Practice, pp. 975-977, John Wiley & Sons, Inc., publ. (1995).
Ahmad Saleem
Hernandez Andres S.
Washburn William N.
Balasubramanian Venkataraman
Bristol--Myers Squibb Company
Rodney Burton
Sun Jing G.
LandOfFree
Non-basic melanin concentrating hormone receptor-1 antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-basic melanin concentrating hormone receptor-1 antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-basic melanin concentrating hormone receptor-1 antagonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2706318