Non-antigenic branched polymer conjugates

Details Non-antigenic branched polymer conjugates Non-antigenic branched polymer conjugates

1997-03-20

1999-07-06

Gulakowski, Randy

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

4241791, 4241941, 42419511, 4241931, 514449, 560182, 549433, 549510, 525 541, 525 5411, 525403, 525408, 530403, 530406, 530408, 530410, A61K 39395

Patent

active

059194553

ABSTRACT:
Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.

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