Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 3,10-dihydroxy-2-naphthacene carboxamide or derivative doai
Patent
1987-07-13
1990-06-19
Medley, Margaret B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
3,10-dihydroxy-2-naphthacene carboxamide or derivative doai
A61K 3165
Patent
active
049354124
ABSTRACT:
Tetracyclines having substantially no effective antibiotic or antibacterial activity and possessing anti-collagen-destructive enzyme activity or anti-collagenase activity and compositions containing the same have been found useful as anti-collagenolytic agents. Such tetracyclines and compositions containing the same are useful in the treatment of periodontal diseases, corneal ulcers, bone deficiency disorders, rheumatoid arthritis diseases characterized by excessive collagen destruction. A special aspect of this invention involves the incorporation of such tetracyclines in animal feed compositions for improved animal nutrition, such as may be evidenced by increased weight gain.
REFERENCES:
patent: 2895880 (1959-07-01), Rosenthal
patent: 3304227 (1967-02-01), Loveless
patent: 3914299 (1975-10-01), Muxfeldt
patent: 4248892 (1981-02-01), Kanamaru et al.
patent: 4371465 (1983-02-01), McGregor
patent: 4457936 (1984-07-01), Draeger et al.
Valcovi et al., Chemical Ab. No. 95:6899.
Brandt, et al., Chemical Ab. No. 92:163746.
Glatz et al., Chemical Ab. No. 91:20178.
Muxfeldt; Chemical Ab. No. 76:140344
Bitha et al., Chemical Ab. No. 72:43253.
Myl'nikova, Chemical Ab. No. 86:66138.
Plakunov, Chemical Ab. No. 80:104410.
Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 6th Ed., MacMillan Publishing Co., Inc., N.Y., 1980, pp. 961-962.
Chemical Abstracts 100:96203a (1983).
Chemical Abstracts 93:142977t (1980).
Chemical Abstracts 76:30596k (1969).
Golub Lorne M.
McNamara Thomas F.
Ramamurthy Nungavaram S.
Medley Margaret B.
The Research Foundation of State University of New York
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