Non-antibacterial tetracycline compositions possessing anti-coll

Details Non-antibacterial tetracycline compositions possessing anti-coll Non-antibacterial tetracycline compositions possessing anti-coll

1987-10-28

1990-06-19

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

3,10-dihydroxy-2-naphthacene carboxamide or derivative doai

A61K 3165

Patent

active

049354116

ABSTRACT:
Tetracyclines having substantially no effective antibiotic or antibacterial activity and possessing anti-collagen-destructive enzyme activity or anti-collagenase activity and compositions containing the same have been found useful as anti-collagenolytic agents. Such tetracyclines and compositions containing the same are useful in the treatment of periodontal diseases, corneal ulcers, bone deficiency disorders, rheumatoid arthritis diseases characterized by excessive collagen destruction. A special aspect of this invention involves the incorporation of such tetracyclines in animal feed compositions for improved animal nutrition, such as may be evidenced by increased weight gain.

REFERENCES:
patent: 3304227 (1967-02-01), Loveless

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