Non-amphetaminic psychostimulating compositions of 1,4-disubstit

Details Non-amphetaminic psychostimulating compositions of 1,4-disubstit Non-amphetaminic psychostimulating compositions of 1,4-disubstit

1976-05-10

1978-06-20

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544397, 544377, 544357, 544121, A61K 31495

Patent

active

040962598

ABSTRACT:
1,4-DISUBSTITUTED PIPERAZINE DERIVATIVES HAVING THE FORMULA ##STR1## wherein R is C.sub.1-3 alkyl, halogen or hydrogen; R.sub.1 is phenyl or C.sub.1-3 alkyl; R' is hydrogen when R.sub.1 is alkyl and is the same as R when R.sub.1 is phenyl; R.sub.2 is hydrogen or C.sub.1-3 alkyl; n is 2-4; n' is 1-4; and A is a group comprising a trivalent organic function which may be acid, ester, nitrile or amide, in which latter case the nitrogen of the amide is part of the ring, and more particularly COOH, COONa, COOCH.sub.3 or COOC.sub.2 H.sub.5. These derivatives or their addition salts with pharmaceutically acceptable acids, have high psychostimulating activity.

REFERENCES:
patent: 2953568 (1960-09-01), Werner
patent: 3205134 (1965-09-01), Biel
patent: 3652568 (1972-03-01), Winter et al.

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