Non-allergenic protective antigens from molds and process for pr

Details Non-allergenic protective antigens from molds and process for pr Non-allergenic protective antigens from molds and process for pr

1981-03-05

1983-06-07

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3900

Patent

active

043870910

ABSTRACT:
Certain isolated fractions, extracted from allergy-causing molds, have been found to be antigenic but non-allergenic, and are able to decrease substantially or prevent the susceptibility to mold allergens of allergic individuals. The antigenic non-allergenic fractions contain protein and carbohydrate and have molecular weights which have been found to vary with the mold source. Increased polyvalent protection can be realized by combining fractions from different molds, e.g. Alternaria with Hormodendrum or Helminthosporium. The extracts are administered parenterally, preferably subcutaneously in isotonic saline.

REFERENCES:
patent: 4138479 (1979-02-01), Truscheit et al.
International Archives of Allergy and Applied Immunology 60: (1979) pp. 229-239-H. M. Vijay et al.
International Archives of Allergy and Applied Immunology 65: (1981) pp. 410-416-H. M. Vijay et al.

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