Non-activated receptor complex proteins and uses thereof

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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514 44, 424 932, 435 6, 435 691, 4353201, 435325, 536 231, 536 235, C12N 1500

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059255668

ABSTRACT:
The invention features a substantially pure ZPR1 polypeptide. For example, a ZPR1 polypeptide that specifically binds to a non-activated membrane-bound receptor (e.g., EGF or PDGF receptors) and specifically binds small nucleolar RNAs (e.g., U3). ZPR1 polypeptides can be isolated from any eukaryote, including mammals (e.g. rodents and humans) and fungi (e.g., S. cerevisiae and S. pombe).

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