Non-A, non-B hepatitis antigen, antigen compositions, vaccine an

Details Non-A, non-B hepatitis antigen, antigen compositions, vaccine an Non-A, non-B hepatitis antigen, antigen compositions, vaccine an

1984-04-26

1987-10-27

Kepplinger, Esther M.

Drug, bio-affecting and body treating compositions

Lymphokine

436543, 436820, 436 5, 435235, 435239, A61K 3912, G21N 33531, C12N 700, C12N 702

Patent

active

047029099

ABSTRACT:
Non-A, non-B hepatitis antigen, antigen compositions, vaccine and assay test for the detection of non-A, non-B hepatitis antigen. The antigen is characterized as having a particle size of about 2.0 nm to about 5.0 nm, a density of from about 1.24 to about 1.30 g/cm.sup.3, contains ribonucleic acid and occurs either free or bound to IgG molecules.
The antigen can be isolated by isopycnic banding and chromatographic fractionation, and preferably by enzymatic digestion, isopycnic banding and chromatographic fractionation.

REFERENCES:
patent: 4291020 (1981-09-01), Tabor et al.
patent: 4395395 (1983-07-01), Tabor et al.
patent: 4464474 (1984-08-01), Coursaget et al.
patent: 4511556 (1985-04-01), Purcell et al.
patent: 4542016 (1985-09-01), Trepo
Alberti, A., Realdi, G., Bortolotti, F., Busachi, C. A., and Badiali, L., presented at the Int. Symp., Non-A, Non-B, Hepatitis, Vienna, Jun. 16-18, 1980.
Alter, H. J., Holland, P. V., Morrow, A. G., Purcell, R. H., Feinstone, S. M., Moritsugu, Y. Lancet 2: 838-841, 1975.
Alter, H. J., Holland, P. V., and Purcell, R. H., Amer. J. Med. Sci., 270: 392-334, 1975.
Arnold, W., Reiter, H. J., Martini, C. A., and Meyer zum Buschenfelde, K. H., Gastroenterology, 79: 1098, 1980.
Avrameas, S., Immunochemistry 6: 43-52, 1969.
Blumberg, B. S., Bull. N. Y. Acad. Med. 40: 377, 1964.
Bradley, D. W., Cook, H. E., Maynard, J. E., McCaustland, K. A., Ebert, J. W., Dolana, G. H., Petzel, R. A., Kantor, R. J., Heilbrum, A., Fields, H. A., and Murphy, B. L., J. Med. Virol. 3: 253-269, 1979.
Coursaget, P., Maupas, P., Levin, P., and Barin, F. Lancet 2: 92, 1979.
Dienstag, J. L., Bhan, A. K., Alter, H. J., Feinstone, S. M., and Purcell, R. H., Lancet 1: 1265-1267, 1979.
Diermietzel, R., Scheirmann, N., Kuwert, E. K., and Goebell, H., presented at the Int. Symp. Non-A, Non-B Hepatitis, Vienna, Jun. 16-18, 1980.
Duermeyer, W., University of California Symposium on Viral Hepatitis, San Francisco, Mar. 8-10, Grune & Stratton, New York, 1984 (in press).
Duermeyer, W., Hellings, J. A., and Stute, R. J. Virol. Methods. 6: 225-232, 1983.
Duermeyer, W., Stute, R., and Hellings, J. A., J. Med. Virol. 11: 11-12, 1983.
Duermeyer, W., Van Der Veen, J., Koster, B., Lancet 1: 823-824, 1978.
Feinstone, S. M., Kapikian, A., and Purcell, R. H., Science 182: 1026, 1973.
Gerety, R. J., Non-A, Non-B Hepatitis, Academic Press Inc., N.Y., 1981.
Gibo, Y., Akahane, A., Koike, Y., Kiyosawa, K., Nagata, A., and Furuta, S., Lancet Hepatogastroenterology Int. Congr. Gastroenterol., 11th, 1980, p. 355.
Haste, G., Vitvitski, L., and Trepo, C. J., Med. Virol. 5: 73-86, 1980.
Hoffnagle, J. H., J. Med. Virol. 7: 315-319, 1981.
Mori, Y., Ogata, S., Ata, S., and Nakano, Y., Lancet 2: 318, 1980.
Ohori, H., Kanno, A., Nagastsuka, Y., Yamada, E., Onodera, Sh., Tateda, A., Abe, Y., Togoh, T., Ishida, N., J. Med. Virol. 12: 161-178, 1983.
Overby, L., Chairez, R., Ling, C. W., and Gitnik, G. L., presented at the Int. Symp. Non-A, Non-B Hepatitis, Vienna, Jun. 16-18, 1980.
Penner, E., Knoflach, P., and Grabner, G., presented at the Int. Symp. Non-A, Non-B Hepatitis, Vienna, Jun. 16-18, 1980.
Poralla, A., Hutteroth, T. H., Arnold, W., Dienes, H. P., Meyer zum Buschenfelde, K. H., Digestion 28: 90-95, 1983.
Prince, A. M., Brotman, B., van der Ende, M. C., Richardson, L., and Kellner, A., Viral Hepatitis, G. N., Vyas ed., The Franklin Institute Press, pp. 633-640, 1978.
Prince, A. M., Trepo, C., Vitvitski, L., Brotman, B., Richardson, L., Huang, C. Y., van den Ende, M. C., and Hantz, O., presented at the Int. Symp. Non-A, Non-B, Hepatitis, Vienna, Jun. 16-18, 1980.
Renger, V. F., Frank, K. H., Porst, H., and Hinkel, K., presented at the Int. Symp. Non-A, Non-B Hep

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