Surgery – Diagnostic testing
Patent
1998-06-25
1999-11-30
Winakur, Eric F.
Surgery
Diagnostic testing
128898, A61B 500
Patent
active
059933887
ABSTRACT:
This invention relates to methods and apparatus for predicting probability of cancer recurrence following radical prostatectomy using predetermined clinical and pathological factors. The invention includes nomograms which can be used preoperatively and postoperatively in patients diagnosed with prostatic adenocarcinoma to aid in selection of an appropriate course of therapy.
REFERENCES:
M. W. Kattan, et al., "Evaluation of a Nomogram Used to Predict the Pathologic Stage of Clinically Localized Prostate Carcinoma", Cancer, vol. 79(3), pp. 528-537 (1997).
R. A. Badalament, et al., "An Algorithm For Predicting Nonorgan Confined Prostate Cancer Using the Results Obtained From Sextant Core Biopsies with Prostate Specific Antigen Level", The Journal of Urology, vol. 156, pp. 1375-1380 (1996).
P. Narayan, et al., "The Role of Transrectal Ultrasound-Guided Biopsy-Based Staging, Preoperative Serum Prostate-Specific Antigen, and Biopsy Gleason Score in Prediction of Final Pathologic Diagnosis in Prostate Cancer", Urology, vol. 46(2), pp. 205-212 (1995).
D.G. Bostwick et al., "Optimized Microvessel Density Analysis Improves Prediction of Cancer Stage from Prostate Needle Biopsies", Urology, vol. 48(1), pp. 47-57 (1996).
A. W. Partin, et al., "Selection of Men at High Risk for Disease Recurrence For Experimental Adjuvant Therapy Following Radical Prostatectomy", Urology, vol. 45(5), pp. 831-838 (1995).
F.E. Harrell, Jr., et al., "Tutorial in Biostatistics; Multivariable Prognostic Models: Issues in Developing Models, Evaluating Assumptions and Adequacy, and Measuring and Reducing Errors", Statistics in Medicine, vol. 15, pp. 361-387, (1996).
A. W. Partin, et al., "The Use of Prostate Specific Antigen, Clinical Stage and Gleason Score to Predict Pathological Stage in Men with Localized Prostate Cancer", The Journal of Urology, vol. 150, pp. 110-114 (1993).
A. W. Partin , et al., "Combination of Prostate-Specific Antigen, Clinical Stage, and Gleason Score to Predict Pathological Stage of Localized Prostate Cancer", JAMA, vol. 227(18), pp.14451451 (1997).
J.J. Bauer, et al., "Biostatistical Modeling Using Traditional Variables and Genetic Biomarkers for Predicting the Risk of Prostate Carcinoma recurrence after Radical Prostatectomy", Cancer, vol. 79(5), pp. 952-962 (1997).
J.J. Bauer et al., "Biostatistical Modeling Using Traditional Preoperative and Pathological Prognostic Variables in the Selection of Men at High Risk for Disease Recurrence after Radical Prostatectomy for Prostate Cancer", The Journal of Urology, vol. 159, pp. 929-933 (1998).
Kattan Michael W.
Scardino Peter T.
Remenick James
Winakur Eric F.
LandOfFree
Nomograms to aid in the treatment of prostatic cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nomograms to aid in the treatment of prostatic cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nomograms to aid in the treatment of prostatic cancer will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1665707