Noise controlled immunoassays

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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436531, 436807, 436809, 436825, G01N 3353, G01N 33543, G01N 33545

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active

048290092

ABSTRACT:
A method for reducing false positives and to assay background noise in solid phase immunoassays utilizes a matrix coated on a solid support, which matrix contains an effective amount of a noise reduction component and an effective amount of noise balancing component. Optimization of the matrix composition is obtained by measuring parameters for its effectiveness which include sensitivity ratio, noise balance ratio, and signal to noise ratio.

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patent: 4582791 (1986-04-01), Khanna
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Seno et al., (1983) Biorheology 20:653-662.
Brenner et al., (1978) Am. J. Physiol. 234:F455-F460.

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