Nogo receptor antagonists

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S809000, C530S388240, C530S350000

Reexamination Certificate

active

08030456

ABSTRACT:
Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same.

REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 3939350 (1976-02-01), Kronick et al.
patent: 3996345 (1976-12-01), Ullman et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4277437 (1981-07-01), Maggio
patent: 4366241 (1982-12-01), Tom et al.
patent: 4399216 (1983-08-01), Axel et al.
patent: 4510245 (1985-04-01), Cousens et al.
patent: 4634665 (1987-01-01), Axel et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4968615 (1990-11-01), Koszinowski et al.
patent: 5168062 (1992-12-01), Stinski
patent: 5179017 (1993-01-01), Axel et al.
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5877293 (1999-03-01), Adair et al.
patent: 5886152 (1999-03-01), Nakatani et al.
patent: 6054297 (2000-04-01), Carter et al.
patent: 6475753 (2002-11-01), Ruben et al.
patent: 6627741 (2003-09-01), Ruben et al.
patent: 6774216 (2004-08-01), Ruben et al.
patent: 6812339 (2004-11-01), Venter et al.
patent: 7119165 (2006-10-01), Strittmatter
patent: 7173118 (2007-02-01), Strittmatter et al.
patent: 7456255 (2008-11-01), Strittmatter et al.
patent: 7465705 (2008-12-01), Lee et al.
patent: 2002/0012965 (2002-01-01), Strittmatter
patent: 2002/0055139 (2002-05-01), Holtzman et al.
patent: 2002/0077295 (2002-06-01), Strittmatter
patent: 2003/0113325 (2003-06-01), Hu et al.
patent: 2003/0113326 (2003-06-01), Hu et al.
patent: 2003/0124704 (2003-07-01), Strittmatter et al.
patent: 2004/0029169 (2004-02-01), Hu et al.
patent: 2005/0048520 (2005-03-01), Strittmatter et al.
patent: 2005/0221420 (2005-10-01), Barske et al.
patent: 2005/0271655 (2005-12-01), Lee et al.
patent: 2007/0065429 (2007-03-01), Lee et al.
patent: 2008/0045926 (2008-02-01), Relton et al.
patent: 2008/0219984 (2008-09-01), Strittmatter
patent: 2008/0274112 (2008-11-01), Lee et al.
patent: 2009/0175850 (2009-07-01), Strittmatter et al.
patent: 2010/0278831 (2010-11-01), Strittmatter
patent: 0 216 846 (1990-01-01), None
patent: 0 256 055 (1991-08-01), None
patent: 0 323 997 (1993-04-01), None
patent: WO 91/17271 (1991-11-01), None
patent: WO 92/01047 (1992-01-01), None
patent: WO 92/09690 (1992-06-01), None
patent: WO 92/15679 (1992-09-01), None
patent: WO 92/18619 (1992-10-01), None
patent: WO 92/20791 (1992-11-01), None
patent: WO 93/01288 (1993-01-01), None
patent: WO 00/32221 (2000-06-01), None
patent: WO 00/73452 (2000-12-01), None
patent: WO 01/51520 (2001-07-01), None
patent: WO 02/29059 (2002-04-01), None
patent: WO 03/002602 (2003-01-01), None
patent: WO 03/018631 (2003-03-01), None
patent: WO 03/031462 (2003-04-01), None
patent: WO 03/035687 (2003-05-01), None
patent: WO 03/089470 (2003-10-01), None
patent: WO 2004/014311 (2004-02-01), None
patent: WO 2004/093893 (2004-11-01), None
patent: WO 2005/016955 (2005-02-01), None
patent: WO 2008/027526 (2008-03-01), None
Chen, et al, 2000, Nature, 403: 434-439.
Rudikoff et al, Proc Natl Acad Sci USA 1982 vol. 79 p. 1979-1983.
MacCallum et al. J. Mol. Biol. (1996) 262,732-745.
Pascalis et al., The Journal of Immunology (2002) 169, 3076-3084.
Casset et al., 2003, Biochemical and Biophysical Research Communications, 307, 198-205.
Vajdos et al., 2002, J. Mol. Biol., 320, 415-428.
Holm et al., 2007, Mol. Immunol, 44, 1075-1084.
Chen et al., 1999, J. Mol. Bio. 293, 865-881.
Wu et al., 1999, J. Mol. Biol. 294, 151-162.
Basso, D.M., et al., “MASCIS Evaluation of Open Field Locomotor Scores: Effects of Experience and Teamwork on Reliability,”J. Neurotrauma 13:343-359, Mary Ann Liebert, Inc. (1996).
Brittis, P.A. and Flanagan, J.G., “Nogo Domains and a Nogo Receptor: Implications for Axon Regeneration,”Neuron 30:11-14, Cell Press (Apr. 2001).
Chen, M.S., et al., “Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1,”Nature 403:434-439, Macmillan Magazines Ltd. (2000).
Domeniconi, M., et al., “Myelin-Associated Glycoprotein Interacts with the Nogo66 Receptor to Inhibit Neurite Outgrowth,”Neuron 35:283-290, Cell Press (Jul. 2002).
Fournier, A.E., et al., “Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration,”Nature 409:341-346, Macmillan Magazines Ltd. (Jan. 2001).
Fournier, A.E., et al., “Truncated Soluble Nogo Receptor Binds Nogo-66 and Blocks Inhibition of Axon Growth by Myelin,”J. Neurosci. 22:8876-8883, Society of Neuroscience with the assistance of Stanford University's HighWire Press™ (Oct. 2002).
Grandpré, T., et al., “Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein,”Nature 403:439-444, Macmillan Magazines Ltd. (2000).
Grandpré, T., et al., “Nogo-66 receptor antagonist peptide promotes axonal regeneration,”Nature 417:547-551, Nature Publishing Group (May 2002).
Grimpe, B., et al., “The Critical Role of Basement Membrane-Independent Laminin γl Chain during Axon Regeneration in the CNS,”J .Neurosci. 22:3144-3160, Society for Neuroscience with the assistance of Stanford University's HighWire Press™ (Apr. 2002).
Jones, L.L., et al., “NG2 Is a Major Chondroitin Sulfate Proteoglycan Produced after Spinal Cord Injury and Is Expressed by Macrophages and Oligodendrocyte Progenitors,”J. Neurosci. 22:2792-2803, Society for Neuroscience with the assistance of Stanford University's HighWire Press™ (Apr. 2002).
Li, M., et al, “Functional Role and Therapeutic Implications of Neuronal Caspase-1 and—3 in a Mouse Model of Traumatic Spinal Cord Injury,”Neurosci. 99:333-342, Elsevier Science Ltd. (2000).
Li, S. and Strittmatter, S.M., “Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery from Spinal Cord Injury,”J. Neurosci. 23:4219-4227, Society for Neuroscience with the assistance of Stanford University's HighWire Press™ (May 2003).
Liu, B.P., et al., “Myelin-Associated Glycoprotein as a Functional Ligand for the Nogo-66 Receptor,”Science 297:1190-1193, American Association for the Advancement of Science (published online Jun. 27, 2002).
Liu, Y., et al., “Transplants of Fibroblasts Genetically Modified to Express BDNF Promote Regeneration of Adult Rat Rubrospinal Axons and Recovery of Forelimb Function,”J. Neurosci. 19:4370-4387, Society for Neuroscience with the assistance of Stanford University's HighWire Press™ (1999).
McKerracher, L., et al., “Identification of Myelin-Associated Glycoprotein as a Major Myelin-Derived Inhibitor of Neurite Growth,”Neuron 13:805-811, Cell Press (1994).
Metz, G.A.S., et al., “Efficient testing of motor function in spinal cord injured rats,”Brain Res. 883:165-177, Elsevier Science B.V. (2000).
Mikol, D.D. and Stefansson, K., “A Phosphatidylinositol-linked Peanut Agglutinin-binding Glycoprotein in Central Nervous System Myelin and on Oligodendrocytes,”J. Cell. Biol. 106:1273-1279, The Rockefeller University Press (1988).
Mukhopadhyay, G., et al., “A Novel Role for Myelin-Associated Glycoprotein as an Inhibitor of Axonal Regeneration,”Neuron 13:757-767, Cell Press (1994).
Noël, D., et al., “High in Vivo Production of a Model Monoclonal Antibody on Adenoviral Gene Transfer,”Human Gene Therapy 13:1483-1493, Mary Ann Liebert, Inc. (Aug. 2002).
Ramon-Cueto, A., et al., “Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia,”Neuron 25:425-435, Cell Press (2000).
Rutishauser, U. and Jessell, T.M., “Cell Adhesion Molecules in Vertebrate Neural Develop

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