Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-07-14
1999-12-07
Davenport, Avis M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530326, 530300, A61K 3800, A61K 3802, C07K 500, C07K 700
Patent
active
059983752
ABSTRACT:
The present invention relates to novel peptides, pharmaceutical compositions containing them, methods for preparing the compounds, use of the compounds for preparing medicaments for treating vasomotor disturbances, in particular the peripheral vasomotor effects known as hot flushes or hot flashes, and to a method of treating vasomotor disturbances.
REFERENCES:
J. Rudinger "Peptide Hormones" J.A. Parsons, ed., University Park Press, Baltimore: 1976, Chapter 1.
Ling, et al., "Morphinomimetic Activity of Synthetic Fragments of beta lipotropin and Analogs" Proc. Natl. Acad.
Grant "Synthetic Peptides: A User's Guide" W.H. Freeman & Company, New York: 1992, p. 45.
Dooley et al., Life Sciences, vol. 59, No. 1, pp. PL23-29, 1996.
Reinscheid et al., J. of Biol. Chem, vol. 271, No. 24, Jun. 14, 1996, pp. 14163-14168.
Johansen Nils Langeland
Madsen Kjeld
Olsen Uffe Bang
Scheideler Mark
Th.o slashed.gersen Henning
Davenport Avis M.
Esq. Reza Green
Novo Nordisk A S
Zelson Esq. Steve T.
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