Nociceptin analogs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S011000, C546S199000, C546S158000

Reexamination Certificate

active

06861421

ABSTRACT:
A compound of the having the general formula (I) or general formula (II):whereinZ, A, B, C, R1, R2, Q, W, and n are as described herein.

REFERENCES:
patent: 3161645 (1964-12-01), Adriaan et al.
patent: 3318900 (1967-05-01), Adriaan et al.
patent: 3325499 (1967-06-01), Poos et al.
patent: 4215119 (1980-07-01), Mentrup et al.
patent: 4329353 (1982-05-01), Stokbroekx et al.
patent: 4344945 (1982-08-01), Teranishi et al.
patent: 4410528 (1983-10-01), Teranishi et al.
patent: 5574044 (1996-11-01), Thompson et al.
patent: 5661169 (1997-08-01), Di Malta et al.
patent: 5760054 (1998-06-01), Huff et al.
patent: 5767118 (1998-06-01), Nargund et al.
patent: 6063796 (2000-05-01), Yang et al.
patent: 6166037 (2000-12-01), Budhu et al.
patent: 6172067 (2001-01-01), Ito et al.
patent: 0092391 (1983-10-01), None
patent: 0921125 (1999-06-01), None
patent: 60120872 (1985-06-01), None
patent: 10330377 (1998-12-01), None
patent: 9710213 (1997-03-01), None
patent: 9740035 (1997-10-01), None
patent: 9854168 (1998-12-01), None
patent: 9929696 (1999-06-01), None
patent: 9936421 (1999-07-01), None
patent: 9948492 (1999-09-01), None
patent: 9959997 (1999-11-01), None
patent: 0006545 (2000-02-01), None
patent: 0107050 (2001-02-01), None
patent: 0144213 (2001-06-01), None
patent: 0220011 (2002-03-01), None
Custers, F.G.J., et al., “Vesamicol and some of its derivatives: Questionable ligands for selectively labelling acetylcholine transporters in rat brain”,European Journal of Pharmacology, 338:117-183, 1997.
Harrison T, et al., “High Affinity, Selective Neurokinin 2 and Neurokinin 3 Receptor Antagonists from a Common Structural Template,”Bioorganic&Medicinal Chemistry Letters.,vol. 8, pp 1343-1348, especially compounds 2d and 3d on p. 1345. (1998).
Takai H, et al., Synthesis and Pharmacological Evaluation of Peperidine Derivatives wtih Various Heterocyclic Rings at the 4-Position, Chemical Pharmaceutical Bulletin, Mar. 1985, vol. 33, No. 3, pp. 1105-1115, especially pp. 1105 and 1106.
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 129:54361, Huff, et al., ‘Preparation of benzisothiazolones and analogs as alpha. 1C. adrenergic receptor antagonist’, 1998, 392146 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 130:95479, Sasaki, et al., ‘Preparation of piperidine derivatives as cell adhesion inhibitors for inflammation inhibitors, metastasis inhibitors, etc.’, 1998, 795478 CAPLUS (Abstract).
Database on STN CADATA (Columbus, Ohio, USA) CA accession: No. 124:176079, Huff, et al., ‘Preparation of heterocycles as alpha-1c adrenergic receptor antagonists’, 1995, 998362 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 81:77786, Klein, et al., ‘Potential analgesics. 3. 1-(4-Piperidinyl)-2-indolinones and -3, 4-dihydrocarbostyrils’,Arch. Pharm.vol. 307 (5), pp 360-365. (1974), 1974, 47786 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 136:53656, Forbes I.T., ‘A short and efficient syntheisis of N-substituted indol-2-ones (oxindoles)’,Tetrahedron Let.,(2001),vol. 42 (39), pp. 6943-6945, 2001:674545 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 135:195564, Tsushima, et al., ‘Preparation of phenoxalkylamine derivatives useful as opioid delta receptor agonists’, WO 2001/60796 (2001), 2001, 617978 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 135:272955, Tsushima, et al., ‘Preparation of diphenylalkylpiperidine derivatives useful as opioid delta receptor agoinsts’, 2001:713309 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 130:223167, Budhu, et al., ‘Preparation of piperidinylpyrrolidins as modulators of chemokine receptor activity’, 1999:172595 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 95:203828, Bianchi, et al., ‘Compounds with antiulcer and antisecretory activity. I. 3-Aryl-benzimidazolin-2-ones and -thiones’,Eur. J. Med. Chem, 16(4), pp. 321-326 (1981), 1981:203828 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 73:445405, Ogata, et al., ‘Organic photochemical reactions. VII. Photolyisis of 1-benzyl-2-ethylbenzimidazole 3-oxide’,Chem. Pharm Bull, 18(5), pp. 964-969, (1970), 1970:445405 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 95:177993, Guiliano, et al., ‘Spectroscopic studies of 2-oxo-2, 3-dihydrobenzimidazole and some N-monosubstituted o r N,N′ -disubstituted derivatives’,App. Spectrosc.,(1981), 35(5), pp. 486-488, 1981:577993 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio, USA) CA accession: No. 134:353434, Nakamura, et al., ‘Synthesis of a regio-isomer of kealiiquinone, a marine benzimidazole alkaloid’,J. Chem. Soc. Japan, (2001), (4), pp. 429-436, 2001:112633 CAPLUS (Abstract).
Database on STN CASDATA (Columbus, Ohio) CA accession: No. 125:58298, Suzuki, et al., ‘Preparation of heterocycle-containing amides as 5-HT4 agonists’, PCT Int. Appl., p. 122 (WO 96/05166), 1996:393911 CAPLUS (Abstract).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Nociceptin analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nociceptin analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nociceptin analogs will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3412618

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.