Noc2 knockout mouse

Details Noc2 knockout mouse Noc2 knockout mouse

2007-01-23

2007-01-23

Crouch, Deborah (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

C435S354000, C800S003000

Reexamination Certificate

active

11095668

ABSTRACT:
Disclosed are a mouse homozygous or heterozygous for the defect of the Noc2 gene, and a tissue and a cell of the mouse. The Noc2 knockout mice, which exhibit stress-related insulin hyposecretion and accumulation of secretory granules of increased size and irregular shape in exocrine cells, provide a test system used in the development of therapeutic drugs for related disorders.

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