Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1999-09-10
2000-12-12
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, A61B 5055
Patent
active
06159444&
ABSTRACT:
A method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature.
REFERENCES:
patent: 5545396 (1996-08-01), Albert et al.
patent: 6042809 (2000-03-01), Tournier et al.
patent: 6051208 (2000-04-01), Johnson et al.
patent: 6071494 (2000-06-01), Unger
Clarke John
de Souza Ricardo E.
Pines Alexander
Schlenga Klaus
Wong-Foy Annjoe
Hollinden Gary E.
Sartorio Henry P.
The Regents of the University of California
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