NMDA antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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A61K 31675

Patent

active

055004199

ABSTRACT:
The present invention is directed to a new neuroprotective agent. The agent is R-4-oxo-5-phosphononorvaline. This agent is useful in the treatment of ischemic and hypoxic conditions such as stroke.

REFERENCES:
patent: 5326756 (1994-07-01), Whitten et al.
Kehne et al. Euro. J. of Pharmacol., vol. 193 pp. 283-292 (1991).
Kehne et al. Chem Abstr. vol. 114 Entry 199543e (1991).
Whitten et al. J. Med Chem. vol. 33 pp. 2963-2970 (1990).

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