NK1 antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S386000

Reexamination Certificate

active

06878732

ABSTRACT:
A NK1antagonist having the formula (I), with the variables defined herein, which is useful for treating a number of disorders, including emesis, depression, anxiety and cough:

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Holan, et al. “Synthesis and insecticidal properties of ether analogs of DDT-pyrethroids” Chemical Abstracts Service, Columbus, Ohio, US, retrieved from STN Database accession no. 106:214159 (1986).
Heal, “Sibutramine: A novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine”International Journal of Obesity22, Suppl. No. 1:S18-S28 (1998).
PCT International Search Report dated Jul. 2, 2003 for corresponding PCT Application No. PCT/US03/07633.

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