NK-1 receptor antagonists and 5HT.sub.3 receptor antagonists for

Details NK-1 receptor antagonists and 5HT.sub.3 receptor antagonists for NK-1 receptor antagonists and 5HT.sub.3 receptor antagonists for

1994-12-09

1996-11-19

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514305, 514306, 514314, 514315, 514326, 514327, 514329, 514331, 514336, 514344, 514345, 514349, 514350, 514438, 514443, 514444, 514461, 514468, 514816, 514872, A61K 31535, A61K 3144, A01N 4390

Patent

active

055763170

ABSTRACT:
The present invention relates to a method of treating or preventing emesis in a mammal, including a human, by administering to the mammal a 5HT.sub.3 receptor antagonist and an NK-1 receptor antagonist (e.g., a substance P receptor antagonist). It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier, a 5HT.sub.3 receptor antagonist and an NK-1 receptor antagonist.

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