NK 1 antagonists

Details NK 1 antagonists NK 1 antagonists

2006-05-09

2006-05-09

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S207000, C546S208000, C546S209000, C546S210000, C546S212000, C546S214000, C544S124000

Reexamination Certificate

active

07041682

ABSTRACT:
Disclosed are NK1antagonists having the formula:Also disclosed are methods for treating a number of physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough, using the compounds of formula (I).

REFERENCES:
patent: 5620989 (1997-04-01), Harrison et al.
patent: 5760018 (1998-06-01), Baker et al.
patent: 2003/0158173 (2003-08-01), Paliwal et al.
patent: WO 94/10165 (1994-05-01), None
patent: WO 95/19344 (1995-07-01), None
Starykh et al. Relation of structure . . . CA 65:6503 (1966).
Ikizler et al. “Synthesis and biological activity . . . ” CA 129:260395 (1998).
Johnson et al. “A tachykinin receptor antagonist . . . ” CA 125:339038 (1996).
Harrison et al. “preparation of . . . ” CA 122:304898 (1995).
Patani et al. “Bioisosterim; a rational approach in drug design” Che, Rev. 96 3147-76 (1996).
Al-Sehemi et al “Kinetic resolution of amines . . . ” CA 137:5741 (2002).
Tavorath et al. “Drug treatment of chemotherapy induced delayed emesis” CA 126:205 (1996).
McAllister et al. “GR205171 blocks apomorphine . . . ” CA 129:254773 (1998).
Reid et al. “Comparison of the neurokinin-1 antagonist . . . ” CA 134:95359 (2000).
Campos et al. “Prevention of cisplatin-induced emesis . . . ” CA 135:190161 (2001).
Patent Cooperation Treaty International Search Report, PCT/US/03/20783 (CN01576K)—International Filing Date Feb. 7, 2003—3 Pages.

Affiliated with

Also associated with

Rating

NK 1 antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with NK 1 antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and NK 1 antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3544430