Nitroxyl compound and diagnostic media based thereon useful for

Details Nitroxyl compound and diagnostic media based thereon useful for Nitroxyl compound and diagnostic media based thereon useful for

1985-09-24

1989-07-04

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514277, 514359, 530350, 536 11, 546244, 546247, 546306, 546309, 548557, 548565, 548568, 260404, C07D20900, C07D21100, C07D40500, A61K 4400

Patent

active

048450901

ABSTRACT:
Diagnostic media suitable for NMR diagnoses contain compounds of Formula I ##STR1## wherein is a single bond or a double bond, X is the grouping --(CH.sub.2).sub.n -- or, if is a single bond, also the grouping --NHCO(CH.sub.2).sub.n -- wherein n means 0 to 4,

REFERENCES:
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Johnston et al., "Initial Membrane Reaction in the Biosynthesis of Peptidoglycan, Spin-Labeled Intermediates as Receptors for Vancomysin and Ribtocetin" Biochem., vol. 14, No. 12, 1975, 2754.
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J. Comput. Assist. Tomogr., vol. 7, No. 1 (1983), p. 184.
Grodd et al., Abstract, "Comparison of Ionic and Non-Ionic Contrast Media for Renal Enhancement in NMR Imaging," 33rd Annual Meeting, Vanderbilt University Medical School-Nashville, TN, May 12-17, 1985.
Grodd et al., "Ein Neues Nichtionisches Nitroxid-Radikal Als Kontrastmittel in der Kernspintomographie", Digitale Bildgebende Verfahren Integrierte Digitale Radiologie, (1985), pp. 86-91.
Butterfield, "Spin Labeling in Disease," pp. 1-11 and 68-78.
Wolf et al., "Contrast Agents for Magnetic Resonance Imaging," Magnetic Resonance Annual 1985, Raven Press: New York, 1985, pp. 231-266.
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Die Pharmazie, 35:1, Jan. 1980, pp. 10-14, Kertscher et al., Synthesis, No. 7, Jul. 1975, pp. 462-463, Golding et al.
Biochemistry, 14, No. 12, 1975, pp. 2754-2760, Johnston et al.

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