Nitrosourea derivatives of glycosides

Details Nitrosourea derivatives of glycosides Nitrosourea derivatives of glycosides

1975-07-30

1978-04-25

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 4, 536 17, 536 18, 536 53, 424180, C07H 1102

Patent

active

040864154

ABSTRACT:
New nitrosourea derivatives are provided, which possess a high inhibitory activity against the leukemia and tumors with a low toxicity and which are useful for pharmaceutical purposes. The compounds have the formula ##STR1## WHEREIN A represents a glycosyl group, a monovalent residue of methyl glucoside or of alditol, a N-substituted carbamoyloxyalkyl group or a hydroxy-substituted cyclohexyl group when n is 1, or A represents a tetravalent residue of ribostamycin when n is 4 and R represents a lower alkyl or halo-alkyl group and are prepared by treating a compound of the formula ##STR2## WITH A NITROSATING AGENT.

REFERENCES:
patent: 3577406 (1971-05-01), Hessler
patent: 3694428 (1972-09-01), Hardegger et al.
patent: 3767640 (1973-10-01), Suami et al.

Affiliated with

Also associated with

Rating

Nitrosourea derivatives of glycosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nitrosourea derivatives of glycosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitrosourea derivatives of glycosides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2420781